Affinity DataIC50: 0.0200nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as cell growth inhibition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Binding affinity to cereblon in human MDA-MB-231 cells assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Binding affinity to cereblon in human MDA-MB-231 cells assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as cell growth inhibition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as cell growth inhibition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Binding affinity to cereblon in human MDA-MB-468 cells assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Binding affinity to cereblon in human MDA-MB-468 cells assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Binding affinity to CRBN (unknown origin) measured by Fluorescent Polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Binding affinity to cereblon in human MDA-MB-468 cells assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Binding affinity to cereblon in human MDA-MB-231 cells assessed as cell growth inhibition measured after 4 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as reduction in cell growth inhibition measured after 4 days in ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 120nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 168nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as reduction in cell growth inhibition ...More data for this Ligand-Target Pair
Affinity DataIC50: 211nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as reduction in cell growth inhibition measured after 4 days in ...More data for this Ligand-Target Pair
Affinity DataIC50: 234nMAssay Description:Displacement of fluorescent tracer from NanoLuc-tagged CRBN (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 254nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 259nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 300nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 310nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 324nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 337nMAssay Description:Displacement of fluorescent tracer from NanoLuc-tagged CRBN (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 339nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 376nMAssay Description:Displacement of fluorescent tracer from NanoLuc-tagged CRBN (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPDB
Affinity DataIC50: 382nMAssay Description:Displacement of fluorescent tracer from NanoLuc-tagged CRBN (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 390nMAssay Description:Displacement of fluorescent tracer from NanoLuc-tagged CRBN (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 393nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Binding affinity to cereblon in human RV4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as reduction in cell growth inhibition ...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 419nMAssay Description:Binding affinity to cereblon in human MDA-MB-468 cells assessed as reduction in cell growth inhibition measured after 4 days in presence of 10 uM len...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of CRBN (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 464nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 467nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 468nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 483nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1 -[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1 ,3-dioxo-...More data for this Ligand-Target Pair
Affinity DataIC50: 496nMAssay Description:Binding affinity to cereblon in human RV4:11 cells expressing wild type p53 assessed as reduction in cell growth inhibition measured after 4 days in ...More data for this Ligand-Target Pair